Explain how a substitution mutation could cause an enzyme not to work (5)

The mutation changes the order of bases so there is a different triplet code present. This results in a different amino acid being coded for in the polypeptide chain. This means a different protein with a different tertiary structure is made. The enzymes active site will also be different and no longer complimentary to the substrate. Therefore no reaction can make place as the substrate can not fit into the enzymes active site any more.

EC
Answered by Evie C. Biology tutor

7430 Views

See similar Biology GCSE tutors

Related Biology GCSE answers

All answers ▸

What is active transport the movement of and what does it need to occur? Give some examples of where is might occur in the human body.


How do species change over time?


Describe the function of the Bowmans's capsule


Explain how the use of antibiotics might lead to a resistant strain of bacteria arising.


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2025 by IXL Learning