Explain the process of DNA replication, including the names of vital enzymes

DNA replication is used to copy DNA. This process is semi-conservative, meaning the new double helix contains both a parent and a new strand. The process begins during S phase, where helicase unwinds the DNA helix in a 5' to 3' direction. This breaks the hydrogen bonds between bases. On the leading strand, RNA primase adds primers complementary to the bases on the parent strand. DNA polymerase III then adds dNTPs to complete the strand, which lose two phosphate groups to ensure a continuous formation of the leading strand strand. The primer is removed by DNA polymerase I. On the lagging strand, RNA primase again adds primers, followed by DNA polymerase III adding dNTPs in a 5' to 3' direction. However, this movement is away from the replication fork and does not allow for continuous assembly. Okazaki fragments are therefore left when DNA polymerase I removes the primer. These fragments are joined together by DNA ligase, which makes sugar/phosphate bonds allowing a full strand to be synthesised.

FV
Answered by Farrah V. Biology tutor

1439 Views

See similar Biology IB tutors

Related Biology IB answers

All answers ▸

Compare and contrast animal and plant cells, giving 3 similarities and 3 differences. Answer can be given as an annotated diagram.


Explain the types of enzyme inhibition


Explain the process of human digestion from the mouth to the stomach.


Explain the effect of inhibitors on the activity of enzymes.


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2025

Terms & Conditions|Privacy Policy
Cookie Preferences