How to go about designing a responsive HTML 5 website

Responsive Web Design is about using the right CSS and HTML to resize and hide the content to make it look good on any screen. I have experience in the past building website related projecjts and could offer a great help in the field of Website Development. 

Also what we need to think about is the use of technologies around us, can we make the website much more nicer and interesting with the use of technologies around us ?