What's the difference between Sn1 and Sn2 reactions?

The term Sn is drived from 'nucleophilic substitution reaction'. 1 means unimolecular, and the rate of the reaction only depend on the concentration of one reactant; 2 means bimolecular, and the rate of the reaction depends on both two reactants.

The tricky part is that for Sn1 there are two possible products whereas for Sn2 there only one possible product. Students easily get confused in this part, but if we look at the machenisms of those two substitution reactions, things will become more clearly (with the aid of the graph). There are a lot of factors that will influence whether a reaction will go through Sn1 or Sn2.

However, in A-level, we only need to consider the steric hindrance of the substrate, in other words, is the substrate bulky or not? If it is a bulky substrate, e.g.(CH3)CBr, it will go through Sn1 route as it is hard for nucleophile to approach the centre carbon, and the only way is the Br leaving first. If it is not bulky, Sn2 will take place.

There are also other very interesting factors I can explain, if you want learn more chemistry.

YG
Answered by Yuan G. Chemistry tutor

15095 Views

See similar Chemistry A Level tutors

Related Chemistry A Level answers

All answers ▸

Name and draw the mechanism by which benzene reacts with ethanoyl chloride in the presence of a catalyst. Also explain why benzene undergoes a substitution reaction, rather than an addition reaction.


Predict the number of peaks in a carbon-13 NMR spectrum of the following carbonyl isomers of C5H8O. (i) CH3CH2CH2CH2CHO (ii) (CH3)3CCHO (iii) CH3COCH(CH3)2


The equilibrium N2O4 (g) -->--< 2NO2 (g) is set up when N2O4 dissociates. When 0.0370 moles of N2O4 dissociates at 25 degrees in a 0.5dm3 sealed container, 0.0310 moles of N2O4 remains at equilibrium. Calculate the value of Kc for this reaction.


What are the features of a dynamic equilibrium?


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning