Compare competitive and non-competitive inhibition

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Competitive inhibition:

-Single active site for binding of substrate/competitive inhibitor

-binding does not change the strutcure of protein

-inhibition reversible by increasing substrate concentrtation that displaces competitive inhibitor

Non competitive

-non competitive inhibitor bind in a site close to the active site

-binding of non competive inihibitor causes structural change of protein which prevents substrate from binding in active site

-inhibition not reversible by increasing substrate concentration 

Tatiana S. IB Biology tutor, IB Chemistry tutor

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