What are monoclonal antibodies and how are they used in treatment?

Monoclonal antibodies are antibodies artificially derived from a single B cell clone (i.e. specific antibodies)An animal (typically a mouse) is injected with an antigen and produces antigen-specific plasma cellsThe plasma cells are removed and fused (hybridised) with tumour cells. Recall that tumour cells are capable of endless divisions.This leads to the formation of a hybridoma cell which is capable of synthesising large quantities of monoclonal antibodies
Monoclonal antibodies are used in treatment are called therapeutic monoclonal antibodies and are usually given to patients suffering of harmful infectious disease and requiring a more intense immune responsee.g. when infected by rabies (which may be fatal) injection of monoclonal antibodies constitutes an effective emergency treatment.e.g. in some cases of cancer, the body does not recognise the tumour as harmful. Therefore injection of monoclonal antibodies allow to target the tumour

Answered by Maxime G. Biology tutor

749 Views

See similar Biology IB tutors
Illustration of a video tutorial

Need help with Biology?

One to one online tuition can be a great way to brush up on your Biology knowledge.

Have a Free Meeting with one of our hand picked tutors from the UK’s top universities

Find a tutor

Related Biology IB answers

All answers ▸

Explain the process of transcription in Eukaryotes


What are the similarities and differences between photophosphorylation and oxidative phosphorylation?


How do the hydrophobic and hydrophilic properties of phospholipids help maintain the structure of cell membranes?


Explain the stages of aerobic respiration that occur in the mitochondria of eukaryotes. [8]


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2022

Terms & Conditions|Privacy Policy