How is an action potential formed when the neurone is stimulated?

When the neurone is stimulated, the Na+ channels open to allow influx of sodium ions down its electrochemical gradient. This makes the inside of the cell less negative. When threshold voltage (-55mV) is reached, depolarisation occurs. This occurs because the cell becomes much more permeable to Na+ ions, so the massive influx depolarises the membrane. When the membrane voltage reaches +30mV, the Na+ channels close and the K+ ion channels open. This causes K+ ions to flow out of the cell, making the cell more negative. This is called repolarisation. The K+ channels are slow to close, and hyperpolarisation occurs, where the membrane voltage decreases to below resting potential. Eventually, K+ channels close and the sodium-potasium pump restores the membrane back to its resting potential.

IC
Answered by Ismael C. Biology tutor

2961 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

What is the difference between Evolution and Natural Selection?


Describe the synthesis of ATP in oxidative phosphorylation


Describe how the lac operon works when lactose is both present and absent.


Describe the structure of an antibody


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning