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What is the Hardy-Weinberg Principle and how can I use the equation to help answer exam questions?

The Hardy-Weinberg principle is a mathematical model that predicts the frequencies of alleles in a population that won't change from one generation to the next. 

There are certain conditions that must be met by the population for Hardy-Weinberg to work 

e.g. There must be random mating amongst the population

e.g. There must be no immigration or emigration in and out of the population.

p2 + 2pq + q= 1

..where p= the frequency of the dominant allele

q= the frequency of the recessive allele

[p2 = frequency of homozygous dominant genotype]

[2pq = frequency of heterozygous genotype]

[q2 = frequency of homozygous recessive genotype]

Using this equation, you can input known values of frequency of alleles or of genotype to find the frequency of genotype of another category of the population. 

Victoria S. GCSE Biology tutor, A Level Biology tutor, GCSE Maths tutor

2 years ago

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