How do antibodies work?

Foreign cells that enter the body have antigens on the outside of them which will be complementary to a specific antibody. The antibody can bind to the antigen, forming an antigen-antibody complex, and this causes agglutination of the pathogens so they can be destroyed more easily by phagocytosis, carried out by macrophages. The pathogen is engulfed and held within a phagocytic vacuole, which fuses with a lysosome that contains lysozymes. These lysozymes are enzymes which can break down the pathogen and allow the antigens to be presented by the phagocyte, activating B cells and T cells. Antibodies also neutralise toxins released by pathogens using antitoxins.

More antibodies are produced when B cells are activated by the antigens being presented by these antigen-presenting cells. One B cell divides into plasma cells, which can all produce many monoclonal antibodies against the specific antigen.

LB

Related Biology GCSE answers

All answers ▸

What adaptations do animals have to help them survive in specific environments?


Write the balanced symbol equation for aerobic respiration


How are plant cells adapted for photosynthsis


If populations of species become isolated, new species are more likely to develop. Explain why. (2 marks)