Explain how the DNA of a Eukaryote is replicated

To replicate the DNA of a eukaryotic cell, the double helix structure must first be unwound to present the base pair sequence. This is done using DNA helicase (this enzyme breaks the hydrogen bonds connection the base pairs so separating the 2 strands making up the double helix structure).

Once unwound, the now presenting bases on both now separated strands can bind with free floating nucleotides found in the nucleolus of the cell (where this process is occurring). Each base will pair with its complementary base, (A and T, C and G) and will be held together using hydrogen bonds.

This will create 2 new strands connected to each of the old ones (semi-conservative replication) however only hydrogen bonds will be holding these new strands together. The sugar phosphate backbone (see the structure of a nucleotide) must be formed, and this is done by the enzyme DNA polymerase.

Thus, 2 identical double strands are formed, each made up of a new and old strand.

OW

Related Biology A Level answers

All answers ▸

How does a vaccine lead to the production of antibodies against a virus?


Outline the typical immune response triggered when a pathogen infects the body


Tom is an expactant father who is worried that he will pass on his Haemophilia A, an X linked recessive disease, to his offspring. The mother is homozygous dominant. Explain why his 1st generation offspring will not be affected by the condition.


What is the difference between the humoral and cell-mediated immune repsonses?