As one of the body's homeostatic mechanisms, blood glucose levels are controlled for by the hormone insulin. Explain how the regulation in blood glucose differs in a healthy individual and in somebody with type 1 Diabetes?

After the ingestion of a meal containing carbohydrate, glucose is released into the blood stream from the gut. An increase in blood glucose stimulates the secretion of the hormone, Insulin from the pancreas which in a healthy individual, signals the liver, muscle and fat cells to take in glucose from the blood which helps to maintain glucose at a constant level in the body. Insulin therefore acts by aiding the absorption of glucose into the body's cells to be used for energy. If the body has sufficient energy, insulin signals the liver to take up glucose and store it as glycogen, a process called glycogenesis. Blood glucose levels subsequently reduce.  Individuals with type 1 Diabetes, are deficient of insulin resulting from the autoimmune destruction of the Beta-cells in the pancreas. Therefore blood glucose levels are naturally unregulated resulting in the dangerous rise in blood glucose called hyperglycemia, which can result in many health complications if the condition isn't controlled for by regular exercise or insulin therapy. Type 1 diabetic individuals who poorly manage their blood glucose levels, have an increased risk of death.

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Answered by Hannah S. Biology tutor

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