Describe the process of oxidative phosphorylation

There are four main electron carrier protein complexes in the inner mitochondrial complex, which use the energy from the transfer of electrons to pump H+ into the intermembrane space, this is known as the electron transport chain. H+ and e- are generated from the breakdown (re-oxidisation) of NADH and FADH2 (at Complexes I and II respectively) and are produced by the Krebs cycle. The H+ build up in the intermembrane space creates a proton gradient which causes the H+ ions to diffuse through a protein channel associated with ATP synthase which uses the gradient's energy to facilitate the formation of ATP from ADP + Pi. The electrons left over from the transport chain react with oxygen, as the terminal reaction of the electron transport chain and create oxygen radicals. These oxygen radicals react with the H+ ions in the mitochondrial matrix to produce water.

TB

Related Biology A Level answers

All answers ▸

What is oxidative phosphorylation?


In a population of 1000 lemmings there are two alleles for skin colour, the dominant colour being cream (C) and the recessive being white (c). 350 individuals have white skin. Use Hardy-Weinberg to predict the number of homozygous recessive individuals.


If a gene mutation is associated with the development of Alzheimer's Disease (e.g. E280A), how might a high frequency develop in a population and why wouldn't natural selection decrease it?


Describe the structure of proteins.