Describe how ACh transmits nerve impulses across Cholinergic Synapse

1.AP arrives at the presynaptic neurone2.AP stimulates voltage gated Ca ion channels to open3.Increased permeability of Ca ion channels causes synaptic vesicles to fuse with presynaptic membrane4. Exocytosis occurs - vesicles release neurotransmitter Acetylcholine (ACh) into synaptic cleft5. ACh diffuses across the synaptic cleft and binds to cholinergic receptors on the postsynaptic membrane6. Na ions channels open in the postsynaptic neurone7. Influx of Na ions causes depolarisation and if threshold is reached an AP8. Enzyme Acetylcholinesterase breaks down ACh so the response does not keep happening.

NA
Answered by Natasha A. Biology tutor

2657 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

A biologist has a small pond containing goldfish in her garden. On a sunny day, more pondweed is at the surface of the water but on a cloudy day, less pondweed is at the surface. Suggest an explanation for this observation


Describe the effects of nitrogen and phosohorus fertiliser leaching into a lake


Why is it difficult for a baby to get enough oxygen to their tissues when there is a hole between the left and right ventricles?


What is saltatory conduction?


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2025

Terms & Conditions|Privacy Policy
Cookie Preferences