What's the difference between the 'lock and key' and 'induced fit' models for enzymes?

The lock and key hypothesis suggests that the enzyme has a fixed shape/structure and the substrate has to fit into this exactly for catalysis to occur. The induced fit hypothesis is different in that it suggests the enzyme is slightly flexible and can mould around the substrate to adopt the correct shape - its shape is induced.

Answered by Harriet W. Biology tutor

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