Use your knowledge of the actin and myosin mechanism of muscle contraction to explain how a vesicle might be "walked" along the cytoskeleton of a cell.
ATP binds the myosin head in its resting state. ATP is hydrolysed to ADP + Pi, releasing energy. This changes the conformation of the myosin head, cocking it. The myosin head reattaches to the actin molecule further along the filament. ADP + Pi dissociate from the myosin head, returning the molecule to its resting conformation. The vesicle is moved further along the actin filament in this motion.
AH
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