How does DNA replication work?

First, the DNA Helicase enzyme ‘unzips’ the two stranded DNA by breaking the hydrogen bonds present between the complimentary base pairs on the two opposing strands. Then this leaves two exposed strands, allowing free DNA nucleotides to each form hydrogen bonds with its complementary base on the exposed strand. DNA Polymerase then goes along and connects the free nucleotides in each strand together to form a long phosphodiester backbone. Once replication has finished, all the enzymes detach and we end with two identical copies of the DNA, each with one original and one new strand.

TK
Answered by Tarek K. Biology tutor

3069 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

What is the difference between an endocrine and exocrine gland?


Describe the role of DNA polymerase in DNA replication.


What is the difference between hydrophillic and hydrophobic molecules?


What are the methods of immobilising enzymes?


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning