How does pH affect the rate of reaction on an enzyme?

Optimum pH for enzymes in the human body is 6. It's a bell shaped Graph. At Higher or lower pH, the alkalinity/acidity denatures the enzyme, which changes the shape of the active site, and so the substrate cannot fit. Therefore, the enzyme-substrate complex cannot be made, and so the enzyme does not work.

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Answered by Max H. Biology tutor

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