What is the difference between eukaryotic cells and prokaryotic cells?

The main difference between eukaryotes and prokaryotes is that eukaryotic cells contain membrane-bound organelles (this includes a nucleus). Eukaryotes can be a single-celled or multi-celled organisms, such as a bee, or an elephant, or a human. An easy way to remember this is YOU are an Eukaryote! Prokaryotic cells can only be single-celled and do not have a nucleus nor any other membrane-bound organelles. Prokaryotes, as you would expect, are much smaller in comparison with eukaryotic cells, an example being bacteria. The similarities between the two is that both types of cell: 1) contains DNA as a heritable genetic material, 2) can reproduce, 3) can transcribe DNA into RNA and use that RNA to make proteins.