When people have liver failure they may get swollen legs due to oedema. Explain the processes behind this.

The liver is responsible for making proteins found in the blood which help to maintain it's "oncotic pressure", the 'pull' factor that holds water inside the blood vessels. These proteins cannot pass through the blood vessels into the tissues, so they hold water within the blood. When the liver fails, these proteins are not produced and thus the 'oncotic pressure' of the blood falls; without this, water leaks out of the blood vessels through osmosis, as the tissues now have a higher oncotic pressure. Leakage of water into the tissues causes them to swell up, producing the oedema.

JI

Related Human Biology A Level answers

All answers ▸

Approximately how long is a double-stranded DNA molecule with a molecular weight of 3x10^9 g/mol? Assume the molecular weight of one nucleotide is 333 g/mol, and that there are 10 base pairs for each turn of the DNA helix equalling 3.4nm in length.


If there are 30 bases of cytosine in DNA, then how many bases of thymine are there?


What is the role of a vitamin in the body?


What are the stages of meiosis?