When people have liver failure they may get swollen legs due to oedema. Explain the processes behind this.

The liver is responsible for making proteins found in the blood which help to maintain it's "oncotic pressure", the 'pull' factor that holds water inside the blood vessels. These proteins cannot pass through the blood vessels into the tissues, so they hold water within the blood. When the liver fails, these proteins are not produced and thus the 'oncotic pressure' of the blood falls; without this, water leaks out of the blood vessels through osmosis, as the tissues now have a higher oncotic pressure. Leakage of water into the tissues causes them to swell up, producing the oedema.

JI
Answered by Joy I. Human Biology tutor

3018 Views

See similar Human Biology A Level tutors

Related Human Biology A Level answers

All answers ▸

Describe the role of the heart and lungs in the oxygenation of blood in humans. Why is oxygen is essential for the functioning of the human body.


Describe the effect of calcium ions on tropomyosin and actin in skeletal muscle.


Name the lobes of the cerebrum and describe their function briefly. Also describe the function of the cerebellum and the brainstem.


When blood enters an arteriole, fluid leaks out into the tissues. Explain how most of the fluid is returned to the arteriole.


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning