How is a nerve impulse transmitted across a cholinergic synapse?

Action potential reaches pre-synaptic knob.This stimulates voltage gated Ca2+ channels to open and Ca2+ to diffuse in.This causes vesicles containing ACh to bind to the pre-synaptic membrane and release ACh into the synaptic cleft.ACh diffuses across the cleft and binds to cholinergic receptors on the post-synaptic membrane.This causes Na+ channels to open and Na+ to diffuse into the post synaptic knob causing depolarisation.Depolarisation causes an action potential to be fired.

AM
Answered by Amelie M. Biology tutor

3130 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

How does the kidney work in homeostasis?


How is water reabsorption carried out in the kidney?


Where do all the stages of respiration (aerobic and anaerobic) happen?


Explain How Macrophage becomes an Antigen presenting cell


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning