Describe the process of DNA replication

DNA replication is semi-conservative, meaning existing strands are used as templates for new strands. The DNA is separated (unwinds) by the enzyme helicase. This enzyme breaks the H bonds between nucleotides. Topoisomerase breaks the DNA ahead of the opening of the replication fork before it gets to tight (to reduce tension). An enzyme called primase starts a short RNA chain from scratch using RNA nucleotides. Now DNA polymerase can build the new DNA strand using complementary base pairing (Adenine - Guanine, Cytosine - Uracil) in the 5' to 3' direction.
The second strand is built up by joining segments called Okazaki fragments using the enzyme DNA ligase. This occurs in the 3' to 5' direction and makes phosphodiester bonds.
This results in the formation of 2 identical DNA complexes.

KO
Answered by Katherine O. Biology tutor

2742 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Describe the process of glycolysis


Describe The Structures of different sugars, and why these different features are useful.


Explain the process of Glycolysis and the products required and formed at each stage?


Describe the process of semi-conservative replication.


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning