Explain the differences between the lock-and-key mechanism of enzyme action and the induced fit model

The lock-and-key mechanism of enzyme activation involves the active site of the enzyme fitting perfectly with the substrate molecule and the subsequent reaction being catalysed biologically. However, the induced fit model suggests that the active site of the enzyme must first mould and change shape slightly to accommodate the substrate molecule before combining and catalysing the reaction.

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Answered by Caitlin O. Biology tutor

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