Explain the process of DNA translation

  • Google+ icon
  • LinkedIn icon
  • 666 views

[Pre-initiation - Specific enzymes catalyse the attachment of amino acids to tRNA, requires ATP]

1) The small ribosomal subunit binds to the 5' end of mRNA and finds the (AUG) start codon 

2) Via complementary base paring, tRNA anti-codon binds to mRNA codon

3) Large ribosomal subunit aligns itself to the tRNA molecule at its P-site, forming a complex subunit

4) At the large subunits A-site another tRNA enters, attaching itself via complementary base paring

5) Complex catalyses reation covalently binding animo acids attached to tRNA in P and A-site

6) The ribosome moves along one codon position, this shifts the deacetylated tRNA to the E-site where it is ejected

7) New tRNA molecule attaches enters the newly emptied A-site and the process is repeated

8) This continues until the ribosome reaches a stop codon on the mRNA

9) Protein may undergo final modifications by other cellular machinery before becoming functional

Hans S. IB Biology tutor, GCSE English Language tutor, GCSE Chemistry...

About the author

is an online IB Biology tutor with MyTutor studying at Edinburgh University

Still stuck? Get one-to-one help from a personally interviewed subject specialist.

95% of our customers rate us

Browse tutors

We use cookies to improve your site experience. By continuing to use this website, we'll assume that you're OK with this. Dismiss

mtw:mercury1:status:ok