How is an Action Potential produced in a neurone?

It is all to do with the movement of ions in and out of the neurone cell, which changes the potential difference accross the cell's membrane. 

- In a neurone's resting state, the inside of membrane is more negative than the outside of the membrane. It has a RESTING MEMBRANE POTENTIAL of -70mV

1) A stimulus excites the neurone. 

2) This causes sodium channels in the membrane to open. Positive sodium channel diffuse INTO the neurone down a concentration gradient. 

3) Due to the influx of positive ions, the membane potential becomes LESS NEGATIVE. This is called depolarisation. 

4) At a membrane potential of around +40mV, sodium channels close and potassium channels open. Positive potassium ions diffuse OUT of the neurone. The membrane potential becomes MORE NEGATIVE again untill it reaches the resting poteneial of -70mV. 

This sequence of events is called an ACTION POTENTIAL.

LS
Answered by Lucy S. Biology tutor

4104 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

What are enzymes? What is the importance of enzymes for living beings?


Describe and explain what happens to enzyme activity as the pH is decreased below the optimum pH.


What is the function of the Loop of Henle?


During large heart attacks the chordae tendineae can be damaged. Use your knowledge of the heart’s structure and the diagram below to to explain how damage to these structures may lead to backflow of blood from the right ventricle to the right atrium.


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2025 by IXL Learning