What is the cAMP cascade and where does it occur?

The cAMP cascade describes an intracellular process that occurs upon activation of glucagon and adrenaline receptors. Glucagon receptors are present mainly in the liver, where they activate enzymes that convert glycogen, glycerol, and amino acids to glucose. Thus, the liver is the main place that releases glucose into the blood once a person is in the fasted state. Adrenaline receptors are present throughout the body, and in the heart for example, they respond with the cAMP cascade to result in increased heart rate. A summary of the cascade is as follows:The hormone binds to its receptor -> this activates the enzyme adenylate cyclase -> the enzyme catalyses the following reaction: ATP -> cyclic AMP (cAMP) -> this activates a protein called protein kinase A. This goes on to phosphorylate and thus activate the enzymes in question.

FF
Answered by Fareema F. Biology tutor

9428 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Outline the "Sliding Filament Theory" of muscle contraction.


How can a child have cystic fibrosis when neither of the parents have the disorder? (5 Marks)


Describe how a gene is used to synthesise a polypeptide


Explain the role of inorganic ions in the body.


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning