Why does a base substitution in DNA not always result in the formation of non-functional proteins?

Protein structure is determined by amino acid sequence. Each amino acid is coded for by a triplet of RNA bases. These are transcribed from a DNA molecule. If a DNA base is substituted for another base, then the RNA triplet codon produces in transcription will differ. However as DNA is degenerate, there is more than one codon for each amino acid, so the amino acid coded for in the transcribed DNA may not be changed. If the amino acid now coded for by the DNA is changed then the protein produced will be non-functional as it will not fold correctly.

AR
Answered by Abby R. Biology tutor

3818 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Nitrates and phosphates from fertiliser applied to crops may enter ponds and lakes. Explain how nitrate may cause the death of fish in fresh water.


What is the difference between an allele and a gene?


What are the limiting factors of Photosynthsis


Describe the process of PCR, including what is needed.


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning