Why does a base substitution in DNA not always result in the formation of non-functional proteins?

Protein structure is determined by amino acid sequence. Each amino acid is coded for by a triplet of RNA bases. These are transcribed from a DNA molecule. If a DNA base is substituted for another base, then the RNA triplet codon produces in transcription will differ. However as DNA is degenerate, there is more than one codon for each amino acid, so the amino acid coded for in the transcribed DNA may not be changed. If the amino acid now coded for by the DNA is changed then the protein produced will be non-functional as it will not fold correctly.

AR
Answered by Abby R. Biology tutor

3790 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Describe the process of Oxidative Phosphorylation in the light dependent stage of photosynthesis


Explain these 3 terms in relation to cells and osmosis: isotonic, hypertonic and hypotonic?


Explain the concept of natural selection. Give an example.


How do I tackle questions that seem only vaguely related to the course I've covered?


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning