Why does a base substitution in DNA not always result in the formation of non-functional proteins?

Protein structure is determined by amino acid sequence. Each amino acid is coded for by a triplet of RNA bases. These are transcribed from a DNA molecule. If a DNA base is substituted for another base, then the RNA triplet codon produces in transcription will differ. However as DNA is degenerate, there is more than one codon for each amino acid, so the amino acid coded for in the transcribed DNA may not be changed. If the amino acid now coded for by the DNA is changed then the protein produced will be non-functional as it will not fold correctly.

AR
Answered by Abby R. Biology tutor

3242 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Why is the resting membrane potential of a neurone negative when there are positive ions inside the cell?


What are the functions of the Kidneys?


What features of the nephron allow ultrafiltration to take place in the kidneys?


Explain why haemoglobin in Sickle Cell Anaemia is less effective at carrying oxygen.


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2025

Terms & Conditions|Privacy Policy
Cookie Preferences