Describe the process of DNA replication

DNA replicates via semi-conservative replication. This means one strand acts as the template strand. The enzyme DNA Helicase breaks the hydrogen bonds between base pairs in DNA. This unwinds the DNA, exposing the template strand. DNA free nucleotides are able to bind to the exposed template strand via complimentary base pairing. This process allows hydrogen bonds between bases to form. The sugar-phosphate backbone is formed by the formation of phosphodiester bonds between the phosphate group of one nucleotide and the deoxyribose sugar of the next nucleotide. This is catalysed by the enzyme DNA Polymerase, in the 5' to 3' direction.
Extension: This occurs continuously on the leading strand, but forms fragments called Ozaki fragments on the lagging strand. The fragments are then joined by DNA ligase.

JD
Answered by Joanna D. Biology tutor

2617 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

State and explain the principles of the Polymerase Chain Reaction (PCR)


Explain how a mutation can cause cancer.


Explain how the alveoli create a surface for efficient gaseous exchange


Describe the structure of the human gas exchange system and explain how we breath in and out.


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2025 by IXL Learning