Describe how negative feedback is used to control blood glucose concentration

Blood glucose concentration levels fluctuates depending on what has been eaten and how much activity has been done. alpha and beta (B) cells in the pancreas detect change in the blood glucose concentration. If blood glucose concentration gets too high beta cells release insulin directly into the blood where it targets the liver. The insulin causes liver cells to absorb more glucose from the blood and convert glucose to glycogen for storage as well as increase the use of glucose in respiration.If blood glucose concentration gets too low alpha cells release glucagon directly into the blood. Glucagon is transported to the liver and binds to specific receptors which activates adenyl cyclase to produce cAMP which acts as a second messenger. This causes the increased conversion of glycogen to glucose and increases the conversion of fats and amino acids to glucose.