How can genetic engineering be used in forensic science and paternity tests?

Genetic fingerprinting is a technique that utilises the presence of highly repetitive non-coding DNA sequences in the human genome, known as variable number tandem repeats (VNTRs). These vary considerably between individuals, with the number of repeats, and therefore size of these VNTRs, being different. Only identical twins possess the same number of VNTRs, as the VNTRs are the result of inheritance from the parents. Therefore, by using endonuclease restriction enzymes to obtain DNA fragments, and these are visualised using radioactive probes complementary to the fragments. A banding pattern is obtained, that can then be used in a variety of contexts.In forensic science, the blood sample from a crime scene will have a genetic fingerprint profile that can be compared to a suspect sample. For a paternity test, as 50% of the genetic material that makes up are genome comes from our father, the banding pattern should have about 50% the same as their progeny if they are the father.

SW

Related Biology A Level answers

All answers ▸

Prokaryotic DNA is smaller than eukaryotic. Please give two other ways prokaryotic DNA differs from eukaryotic.


For a dihybrid cross, how do you find out what proportion of offspring are expected to have a certain genotype?


Compare and Contrast Meiosis and Mitosis


How is protein digested in the human gut?