What are the differences between globular and fibrous proteins?


Just Globular:spherical structure outward facing hydrophilic R-groups, inward facing hydrophobic R-groups, results in being soluble highly specific tertiary structures so can act as enzymes (catalase, alcohol dehydrogenase, RuBisCO), signalling molecules binding to receptors (insulin) and the binding regions of antibodies.primary structure is non-repetitive (mostly)Often can have a quaternary structure of multiple subunits (haemoglobin)Mineral ion cofactors/coenzymes (haemoglobin/chymotrypsin)Just Fibrous: elongated insoluble repeating primary structure (glycine in collagen)Shared: Both have secondary structures, but structures formed differ (alpha helix/beta-pleated sheet vs triple helix)Both have structures determined by H-bonds, hydrophilic/hydrophobic interactions, ionic bonds and disulphide bridges.
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