What is the role of calcium in synaptic transmission?

Calcium is found as an ion, Ca2+ in the extracellular space of the pre-synaptic neuron. The ions enter the neuron through voltage -gated channels after the depolarisation of the pre-synaptic neuron. This causes an influx of calcium ions which help sacs filled with neurotransmitters move to the membrane facing the synaptic cleft. These sacs fuse with the plasma membrane and exocytosis takes place, by which a chemical message is sent to the post-synaptic neuron. The calcium ions are then actively transported out of the neuron to restore the chemical gradient in time for the next depolarisation.

WF
Answered by Wiktoria F. Biology tutor

17625 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

What is the difference between the pulmonary and systemic circuits of the cardiovascular system?


a) Explain how an action potential is passed across a synapse b) Label the graph below with the steps of action potential generation c) The graph shows the results of a study on two groups taking different medication, is the difference significant?


Describe the light-dependent reactions of photosynthesis.


Suggest why some animals (such as snakes) can go for longer periods of time without eating, than humans?


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2025

Terms & Conditions|Privacy Policy
Cookie Preferences