Explain the process of phagocytosis? i.e what type of immune responses can it play a role in/link, what cells are involved, how does it work?

Can be used in adaptive or innate immune response.Can be used to link the two responses, i.e. forming APC which forms MHC complex 2 (endogenous pathway) and presents to complementary CD4+T helper cells. Leading to an adaptive immune response i.e. production of antibodys and B memory cells.Innate: Neutrophils or macrophages.Neutrophils = suicide bombers, rapid cell turnover, first at the scene. They engulf pathogen, release cytotoxic mediators i.e. lysosmes or oxidate radials, killing the pathogen and then die. (collection of neutrophils = puss)Macrophages = Big eaters, line the immunological and non-immunological organs. Can form professions APC which can link innate and adaptive immune response. (Are monocytes in blood stream but turn into macrophages when leaving). Conduct immune responses through release of chemical messengers i.e. cytokines.1) Attaches to complementary pathogen.2) Forms phagosome.3) Realses cytotoxic mediators into vacuole forming phagolysosome.4) Neutrophil: spits out cellular contents.5) Macrophage: combines antigen with MHC complex to form APC.