How does anti-diuretic hormone work to control water loss?

What is it?Anti-diuretic hormone (ADH) is a hormone produced by the hypothalamus and released by the posterior pituitary gland (in the brain), that acts on the nephron in the kidney, specifically the distal convoluted tubule (DCT) and the collecting duct. Effects:It stimulates the cells of these parts of the nephron to put more water channels called aquaporins into their plasma membranes on the luminal side - the side that faces into the tubule. They make the membrane more permeable to water, but not to any ions. Therefore, more water is reabsorbed into the tubule cells and will be taken up into the blood.Purpose: If you are dehydrated, you need to as much water as possible in your blood, to prevent the ion concentrations from getting dangerously high and disturbing the balance of osmosis in the body. Receptors in the hypothalamus detect if this is beginning to happen and stimulate the release of ADH.

ET
Answered by Ellie T. Biology tutor

2457 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

When a new antigen is presented to the immune system, an immune response leads to antibodies are released. The second time this happens it is much faster - explain why


What are the electrical changes in an axon that occur during an Action Potential?


With the aid of a diagram describe the events occurring in the neurone leading to the establishment of an action potential


Explain the concept of natural selection. Give an example.


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning