What are the types and effects of genetic mutations?

Insertion/deletion - one or more nucleotide pairs are put in/taken out of a sequence -> causes frameshift. Duplication - one or more bases are repeated -> leads to frameshift. Inversion - group of bases separate from DNA sequence and rejoin at same position but in reverse order -> forms different amino acids and therefore protein. Translocation - group of bases separate from DNA sequence on 1 chromosome and insert into DNA sequence of another chromosome -> different proteins formed. Some mutations have no effect (neutral) e.g. occurs on non coding part of DNA or silent mutation

ZK

Related Biology A Level answers

All answers ▸

Describe the properties of primary protein structure.


Cystic fibrosis is an autosomal recessive condition. In a population, 0.04% of individuals have the disease. Use the Hardy-Weinberg equation to calculate the number of carriers of cystic fibrosis.


Describe the events that take place to generate an action potential at a nerve synapse


Explain the processes that lead to the contraction of a single muscle