Explain what is meant by temporal and spatial summation in the context of synapses.

Context: We often think of a linear model of one pre-synaptic neurone linking up with one post-synaptic neurone. In reality, the nervous system is a large network, many pre-synaptic neurones may terminate at the same synapse with one post-synaptic neurone. This allows for more complex and controlled signalling. A pre-synaptic neurone's action potential, allows for the release of a set amount neurotransmitter into the synapse, which may not be enough to trigger an action potential in the post-synaptic neurone; which is where spatial and temporal summation become essential. Spatial summation is where multiple pre-synaptic neurones converge on one post-synaptic neurone. The many pre-synaptic neurones releasing neurotransmitter into the synapse has an additive effect and the increased concentration in the synapse is now high enough to trigger a post-synaptic action potential. Temporal summation occurs when a pre-synaptic neurone has several action potentials in a short time period, leading to a building concentration of neurotransmitter substance in the synapse, eventually enough to trigger an action potential in the post-synaptic neurone.

BK
Answered by Bethany K. Biology tutor

4442 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Explain what is meant by epigenetics and how it can inhibit transcription.


Describe how the hormone glucagon helps a healthy individual to maintain their blood glucose concentration correctly.


Describe how filtration of the blood occurs at the Kidney


What are the features of alveolar epithelium which allow efficient gas exchange?


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2025 by IXL Learning