Describe the structure and function of a chemical synapse.

A synapse acts as a junction between cells - either between neurons, or between a neuron and a muscle or gland cell.

Although neurons transmit information via electrical signals, synapses transmit information rapidly via chemicals - these are called neurotransmitters.

When an action potential reaches the end of a neuron (called the pre-synaptic neuron) - called the axon terminus - the change in potential across the cell's plasma membrane stimulates the opening of voltage-gated calcium (Ca2+) channels - causing calcium to rush into the axon terminus. 

This in turn triggers the fusion of synaptic vesicles, which carry the molecules of neurotransmitter, with the plasma cell membrane - this releases the neurotransmitter into the gap (called the synaptic cleft) via exocytosis (the fancy word for transporting 'stuff' such as proteins out of a cell).

The neurotransmitter molecules with then travel across the gap and bind to receptors on the plasma membrane of the post-synaptic cell. This binding then triggers the influx of ions - normally sodium (Na+) into the post-synaptic cell. If this amount of sodium reaches the threshold potential of the neuron, an action potential will be set up in this cell.

BS

Related Biology A Level answers

All answers ▸

How does a stimulus produce an action potential?


Describe and explain what happens to enzyme activity as the pH is decreased below the optimum pH.


Human breast milk is produced and secreted by gland cells. These gland cells have adaptations that include many mitochondria and many Golgi vesicles. Explain the role of these cell adaptations in the production and secretion of breast milk.


Explain how a competitive inhibitor stops an enzyme from working.