How does the lac operon work?

The lac operon has 3 components: the promoter (Binding site for RNA polymerase), the operator (binding site for the repressor) and the structural genes that code for the enzymes required for lactose metabolism. The gene coding for the repressor protein is also located nearby, usually a little before the operon. When lactose is absent, the repressor protein binds to the operator and prevents the RNA polymerase from binding to the promoter. As a result, the enzyme genes cannot be transcribed and the enzymes are not produced. When lactose is present and the enzymes are needed, lactose diffuses into the cell and binds to the repressor protein. This changes the conformation (3D shape) of the repressor. As its shape is different, it can no longer bind to the operator. The RNA polymerase can thus bind to the promoter and the enzyme genes are transcribed and translated.

EB
Answered by Elena B. Biology tutor

20409 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Maltose is hydrolysed by the enzyme maltase. Explain why maltase catalyses only this reaction (3 marks)


Name 2 forms of epigenetic modification, and explain the effect they have on the genotype.


How does gel electrophoresis work to separate DNA fragments of different lengths and how may the lengths of the different strands then be determined?


How does an action potential travel between two neurones?


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning