Why is the resting membrane potential of a neurone negative when there are positive ions inside the cell?

The resting membrane potential inside the neurone (-70mV) is negative relative the outside! This means that even though there are both Na+ and K+ ions inside the cell, there are fewer of them (-70mV fewer) inside the cell compared to the outside. There are also more negative ions, e.g. Cl-, inside the cell compared to outside. The 'membrane potential' (charge) inside the neurone is less than that outside of the neurone, and therefore negative. In summary, the resting membrane potential is negative due to the amounts (concentration) of positive and negative ions inside/outside of the cell, not the charge of the ions themselves.

CS
Answered by Chloe S. Biology tutor

4854 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

The events that take place during interphase and mitosis lead to the production of two genetically identical cells. Explain how.


Outline the process of neuronal communication between two neurones


If DNA inside a cell is damaged, a protein called p53 halts the cell cycle. With this in mind, explain how a p53 gene mutation could cause cancer to develop.


What is the sequence of events for muscle contraction?


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

MyTutor is part of the IXL family of brands:

© 2026 by IXL Learning