# Use the substition u = cos(x) to find the indefinite integral of -12sin(x)cos^3(x) dx

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We are given the substitution to use, so the first step is to differentiate "u" with respect to x

du/dx = -sin(x)

Now, to replace the "dx" in the original integrand with something in terms of "du", we rearrange the differential:

dx = -1/sin(x) du

We substitute this into the original expression we are integrating; this gives:

S -12sin(x)cos3(x) (-1/sin(x)) du

Let's do some simplifying here; the negative signs cancel, and so does sin(x):

S 12cos3(x) du

Now, simplify again using u=cos(x); this gives:

S 12u3 du

This is a simple C1-level integration; integrating with respect to "u" and adding a constant of integration, we get:

3u4 + c

For our final answer, replace "u" with cos(x):

3cos4x) + c

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