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similar in shape to {substrate}fits onto active siteprevents substrate bindinginhibits enzyme activity

directly proportional: increase in [enzyme] will increase rate of reaction

Rate of reaction increases proportional to increase in [substrate]Rate of reaction then levels off/ plateaus not all active sites are being used; adding substrate increases RoR all active sites used/ [enz...

At optimum pH, active site is complimentary to substratepH changes disrupt H-bonds/ ionic bonds

1. Increasing temperature increases KE of molecules1. so more enzyme-substrate (E-S) collisions1. more E-S complexes formed2. Hydrogen/ ionic bonds broken2. Enzyme becomes denatured2. Active site chang...