Describe the process of DNA replication

DNA replication is semi-conservative, meaning existing strands are used as templates for new strands. The DNA is separated (unwinds) by the enzyme helicase. This enzyme breaks the H bonds between nucleotides. Topoisomerase breaks the DNA ahead of the opening of the replication fork before it gets to tight (to reduce tension). An enzyme called primase starts a short RNA chain from scratch using RNA nucleotides. Now DNA polymerase can build the new DNA strand using complementary base pairing (Adenine - Guanine, Cytosine - Uracil) in the 5' to 3' direction.
The second strand is built up by joining segments called Okazaki fragments using the enzyme DNA ligase. This occurs in the 3' to 5' direction and makes phosphodiester bonds.
This results in the formation of 2 identical DNA complexes.

Answered by Katherine O. Biology tutor

1746 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Briefly describe the process of mitosis.


How do I answer questions on the adaptations of the lungs


Explain the structure of DNA.


Explain what is meant by active transport


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2024

Terms & Conditions|Privacy Policy