How is an Action Potential produced in a neurone?

It is all to do with the movement of ions in and out of the neurone cell, which changes the potential difference accross the cell's membrane. 

- In a neurone's resting state, the inside of membrane is more negative than the outside of the membrane. It has a RESTING MEMBRANE POTENTIAL of -70mV

1) A stimulus excites the neurone. 

2) This causes sodium channels in the membrane to open. Positive sodium channel diffuse INTO the neurone down a concentration gradient. 

3) Due to the influx of positive ions, the membane potential becomes LESS NEGATIVE. This is called depolarisation. 

4) At a membrane potential of around +40mV, sodium channels close and potassium channels open. Positive potassium ions diffuse OUT of the neurone. The membrane potential becomes MORE NEGATIVE again untill it reaches the resting poteneial of -70mV. 

This sequence of events is called an ACTION POTENTIAL.

Answered by Lucy S. Biology tutor

2949 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Explain how a very high temperature can stop an enzyme from working.


Albumin (a globular protein) is a solute found in blood plasma. In liver disease, people cannot produce sufficient amounts of albumin. Describe and explain how this change would affect red blood cells.


Explain the mechanism of expiration in the human body.


What types of infectious agents are there?


We're here to help

contact us iconContact usWhatsapp logoMessage us on Whatsapptelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2024

Terms & Conditions|Privacy Policy