Describe the events of the cholinergic synapse

Action potential reaches neurone.Voltage gated Ca²+ channels in the presynaptic membrane open.Calcium ions flow in, pushing acetylcholine filled vesicles to the presynaptic membrane.Vesicles fuse with the membrane.Acetylcholine enters synaptic cleft by exocytosis. Acetylcholine diffuses across synaptic cleft and attached to receptor protein on postsynaptic membrane .In response, postsynaptic membrane's permeability to Na+ ions increases. Sodium ions diffuse in, leading to the depolarisation of post synaptic membrane. Thus, action potential is generated.Acetylcholine is broken down by the enzyme acetylcholinesterase. Choline flows back into presynaptic neurone.

IB
Answered by Ioana B. Biology tutor

5054 Views

See similar Biology A Level tutors

Related Biology A Level answers

All answers ▸

Why may a rise in testosterone above normal cause a subsequent decrease in the hormone?


What is the best method for Biology A level revision?


What is the structure of the human gas exchange system- how do we breathe in and out?


What is a synpase and what is the function of synpases?


We're here to help

contact us iconContact ustelephone icon+44 (0) 203 773 6020
Facebook logoInstagram logoLinkedIn logo

© MyTutorWeb Ltd 2013–2025

Terms & Conditions|Privacy Policy
Cookie Preferences