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Explain how voltage-gated sodium ion channels on the membranes of neurones generate an action potential.

At rest there is a difference in the concentration of sodium ions (Na+) across the membrane of the neurone.

Outside the neurone in the extracellular fluid (ECF) the concentration of Na+ i...

AH
8412 Views

Describe the effect of calcium ions on tropomyosin and actin in skeletal muscle.

Within the muscle fibre tropomyosin is wrapped around actin filaments and it blocks the binding sites for the myosin-heads.

When calcium ion concentration increases, calciu...

AH
16299 Views

Describe the roles of DNA and RNA in determining the sequence of amino acids in proteins.

The sequence of bases (a gene) on DNA determines the order of amino acids that come together to form a polypeptide (protein) chain.

The DNA is 'unzipped' by enzymes called Helicases. This...

AH
4284 Views

People with AF often also have narrowing of the valve between the left atrium and the left ventricle. This causes the wall of the left atrium to become thicker. Suggest why.

With a narrowed (stenosed) AV valve it is more difficult (requires more pressure) for the blood to pass from atrium to ventricle. The blood pressure in the atria is increased.

This means ...

AH
3665 Views

Suggest why an artificial pacemaker can be used to treat AF.

An artificial pacemaker would generate regular electrical impulses in the atria.

The regular electical impulses from the pacemaker are stronger than the irregular impulses from the SAN, t...

AH
3699 Views

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